The information that follows is based on the large-scale systematic review “Preschool wheezing and asthma in children: a systematic review of guidelines and quality appraisal with the Agree II Instrument,”  published in 2020 in the journal Pediatric Allergy and Immunology . The article is the result of the work of a multidisciplinary international team of leading experts in pediatric pulmonology, allergology, and pediatrics, united in the EAACI Task Force on Clinical Practice